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Among 1198 patients with acute liver failure enrolled in a US prospective study between 1998 and 2007, 133 were attributed to drug induced liver injury, but none were linked to pantoprazole or other antiulcer medications).

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Safety and efficacy of use for more than ten days have not been established.

Some alcoholic beverages have benefits such as anti oxidents like red wines (in small amounts, not consuming bottles), whereas grain and rye derived alcoholic beverages (Beer) do more harm then good.

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Overall healing in both treatment groups was 88% of patients (intention-to-treat population), 95% (pantoprazole), and 90% (esomeprazole) (per-protocol population); statistically, this indicates "at least equivalence" between treatments.

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